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No significant difference was observed when the scanning rate was increased from 0
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. Since the frequency of the solvent-exposed secondary structures is smaller than the buried ones (44,45), the above sequential events could be interpreted as follows: the unfolding of the solvent-exposed ß-sheet structures is the earliest event, followed by the formation of aggregates, and finally the unfolding of the other native structures
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. ), by the Center for Biological Modulators of the 21st Century Frontier R&D Program (grant to K
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. Backbone dynamics of calmodulin studied by N-15 relaxation using inverse detected 2-dimensional NMR-spectroscopy: the central helix is flexible
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. As for surgical training, Professor Croce argues that "if anatomical variations in humans form one of the most insidious pitfalls for the surgeons, even for the most expert, is it superfluous to add that such anatomical variations cannot be learned on from animals?" (p
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. Age, gender, baseline depression severity, baseline RAB drug-risk score, and depression type were included as covariates
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. Across both samples, the individual items related to these outcomes in the same directions as the overall scales
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. There were differences in the extent that parental social support was statistically significantly related to adjustment outcomes by gender
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. The majority of the supports named by the adolescents were extended family members such as aunts, uncles, and cousins
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. Correlations for girls are listed in the top row, with thosefor boys underneath
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. These task forces, comprising law-enforcement officers and civilian hires like Coleman, often operate with little oversight
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. Near the base of the ridge slopes are swampy communities of fairly short deciduous and evergreen trees
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. These compounds vary in their effects and utility as well as their abuse potential
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. Many of these AERs occurred in young, healthy adults considered unlikely candidates for such events; 56% of these cases involved individuals less than 40 years old, 92% of these events were related to the use of products marketed for weight-loss and energy purposes, and 5% were related to products marketed for athletic-enhancement purposes
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. Phentermine works by facilitating dopamine and norepinephrine release, while sibutramine facilitates serotonin release and norepinephrine release
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. Sections were incubated at room temperature for 30 minutes and then rinsed with TBS
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. Am J Epidemiol 2000; 152(9):874-883
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. "By 2002, that percentage had dropped to 37 percent, and we feel it has continued to fall since
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. "Clearly, a major reason why an employer or union may want to do this is because it won't have to pay the entire premium," says Norwalk
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. This despite the fact that a decade ago Congress loosened some FDA testing requirements, thus easing industry's ability to bring important new drugs to market quickly
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. INTAC launches Internet parental control software product in ChinaINTERNET BUSINESS NEWS-(C)1995-2005 M2 COMMUNICATIONS LTDINTAC International Inc (Nasdaq: INTN; FSE: WKN 805768), a provider of integrated educational and career development services in China, announced on Friday (11 November) that its subsidiary, Beijing Intac Purun Educational Development Ltd, is launching its Internet parental control software product, the Internet Co-Surfic software (ICS), which is being developed exclusively for the China market along with other related services
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- Although suitable data are not available to establish if there is a direct correlation between the above ANS binding capacity and the actual instability to freeze-thawing (depending on the protein, irreversible damage has been estimated by diverse criteria such as loss of enzymatic activity, degree of aggregation, and loss of secondary or tertiary structure and, further, the outcome is generally influenced by the rates of freezing and thawing), it is a common observation that multimeric enzymes tend to be less stable to freezing than their monomeric counterpart (17)
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. We thus did our experiments with a much higher rf bandwidth (11 kHz) and a shorter rf pulse (0
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. This is called "wraparound" binding because the two domains in CaM wrap around the ?-helical target (8,9)
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. Upon peptide binding, the flexibility of side chains located in the binding sites is redistributed
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.The aggregation reaction was initiated through a pulse of NaCl which induces the molten-globulelike A-state which subsequently assembles into aggregates
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. 6, A-C) and earlier studies (Gursky et al
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. In the triple-helix example that we looked at in detail, the nonnative hydrophobic strips that accelerate the final two-dimensional search are "activated" only when the helices themselves form, at least partially (by the formation of some native interactions) and when their axial rotational degrees of freedom align
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., 1982; Elias and Burgos, 1988; Gonzalez, 1998)
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.2 VitellogenesisOvary firm and yellow or Oogonia and developingoccasionally cream inoocytes still visible, butcolor
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.HDL-cholesterol levels climbed by 28
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. The actions of psychostimulants are mediated through their ability to bind monoamine receptors and/or modulate monoamine transmitter release
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. Her physical examination was unremarkable except for a blood pressure of 155/93 mm Hg
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. Fenfluramine, which increased serotonin levels, was used alone or in combination with the sympathomimetic agent phentermine
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. No changes were seen at 1 year in the three control subjects with moderate/severe aortic regurgitation
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. In: Graham AW, Schultz TK, Wilford BB, eds
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. Directly below these buttons, the "Concept Reference" section held a dropdown list of concept identifiers for all previously viewed concepts and a "Go" button, which displayed details for the concept represented by the selected identifier
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