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Interestingly, considerable conformational changes were observed before the enzyme was fully inactivated by high temperature
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. Experiments conducted with copper-free azurin from Pseudomonas aeruginosa and mutants I7S, F110S, and C3A/C26A correlate the magnitude of the ice-induced perturbation, as inferred from the extent of ANS binding, to the plasticity of the globular fold, increasing with less stable globular folds as well as when the flexibility of the macromolecule is enhanced
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. In practice, the large difference in anisotropy decay between monomeric forms lead to a broad baseline with the contribution of the smaller monomeric forms contributing as a decay curve superimposed onto a baseline
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. In addition to the changes directly related to the intermolecular contact, CD4 binding also induces conformational changes away from the binding interface that are crucial for the subsequent events of viral entry into the host cell
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. degrees in cognitive psychology from the University of Oregon in 1976 and 1978, respectively
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- and thus, it was dominated by the emission of the sole tryptophan residue
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., Framework for Morphological Evolution vis-a-vis Phase Transitions in Polymer Solutions, J
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. First, all data are self-report
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. An Institutional Review Board approved all research protocols
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.Also in January 2004, federal prosecutors agreed to drop 358 of their 362 charges against Tucson pain specialist Jeri Hassman, who pleaded guilty only to four counts of failing to report patients for infractions such as taking a recently deceased relative's OxyContin
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