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Proteins can adopt totally different folded conformations
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. 0) the osmotically stressed solutions were single phase with no visible turbidity
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. The transient nature of oligomeric intermediates of misfolded TTR that later mature into fibrillar aggregates makes them hard to study, and methods to study these species are sparse
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. However, the herein-observed morphological variation after increasing temperature bears a more profound meaning in light of the ongoing debate as to the identity of the protein's aggregation-prone conformation (completely unfolded, or partly unfolded protein) and our own study, showing that under similar conditions, bovine insulin is substantially more unfolded at 70 than at 60°C (Dzwolak et al, 2003)
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. Manuscript submitted 4 April 2003 to Scientific Editor's Office
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. Race may have been a factor in some aspects of the Tulia affair, such as reactions to the arrests in the local press and among the town's white residents
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. The adult supports reported by youth who perceive low parental attachment, were associated with an exacerbation of depressive symptomology and drug use
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. Identifying the TeamFrom a pharmaceutical industry perspective, Purdue is well along the RFID learning curve and ahead of many
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. Which is not to say that gambling is the can't-miss miracle cure-all its boosters often claim it is, or that it doesn't introduce problems and headaches of its own
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. The cardiac valve leaflets showed none of the pathologic changes previously documented with exposure to this anorexiant
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. Weight loss and athletic performance appear to be only modestly improved, for short durations, in the setting of large numbers of (some serious) adverse event reports
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. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus
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. 7 mg/mL^sup -1^ urea hydrogen peroxide and Tris buffer 0
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. 2002), understanding what factors lead to such relationships within the drug abuse treatment sector may thus have vital implications for policy makers and managers
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. However, over the two-year period, the mean number of drug-taking episodes reported by drug users decreased by nearly 70% (p <
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. 12 Together, the pathologic findings underscore the risk-benefit issues of phentermine-fenfluramine use and raise interesting questions regarding the pathogenesis and progression of primary pulmonary hypertension
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- Whenever we pose the question to our students in introductory biology classes, one of them invariably responds: "It's obvious, isn't it? Caves are dark
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." Twenty-eight percent used supplements to manage joint health, 23% each for heart and osteoporosis/bone health, 19% for immune support, 18% for energy and 15% for digestion support
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. Nat Genet 1998; 19:56-59(45) Baumann I, Kolowos W, Voll RE, et al
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. Last year, Andrew Wilton, a leading authority on the 19th-century artist and a former keeper of British art at the Tate, called for the centre not to be built, saying it would resemble a "hideous globule" set in a "daft place"
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. Unfolded, yes, but random? Never! Nat
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. semifasciata (Rosa and Rosa, 1987; Herrera and Cousseau, 1996)
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. In December 1978, Argentine sandperches of both sexes were observed running near Isla Escondida (Ehrlich, personal observ
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.5 ns, resulting in a final increase of 0
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. In each step, chloride salts of appropriate cations (Ca, Fe, and Mg) were dissolved in deoxygenated, CO2-saturated water
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. The fixed eggs were transferred to net wells (mesh size 200 [micro]m, diameter 24 mm, Corning Incorporated, Corning, NY) and washed with 10 mL of distilled water three times
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."Also, several states are beginning to adopt stricter laws regarding the movement of drugs through the supply chain
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.METHODSData SourceThe dataset for this study is a set of 2-year panels constructed from the 1995 to 2000 Medicare Current Beneficiary Survey (MCBS)
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. Lexington, MA: Lexington Books
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. These partial correlations between beneficial and detrimental beliefs may reflect a culturally transmitted belief system about drug treatment and addiction, that is, that treatment is only needed for people who cannot help themselves
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. Continuity into young adulthood
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.Women in the two-drug arm received lapatinib 1,250 mg per day taken continuously and 2,000 mg/[m
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. Psychosocial predictors of current drug use, drug problems, and physical drug dependence in homeless women
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."The facility looks like a finished goods manufacturing warehouse," says Skrinar
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. With helicopters you have to be careful with the amount of torque and collective pitch, but the V-22 has power to spare and these factors are not a "concern
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. Military treaties reaching into the Middle East, including NATO and CENTO, were established
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. Because people play these games with comparatively little computational effort, it is difficult to believe that these players are performing such complex simulations and calculations in real time before making each bet
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. Grant and his Union forces marched into Vicksburg, giving the North control of the Mississippi River
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."That effort led to the launch April 19 of the Pharmacy Quality Alliance
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. We might also imagine, however, that networking may become more likely as organizations develop cooperative skills and become better at obtaining benefits from these ties
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. Racial discrimination and blood pressure: the CARDIA study of young Black and White adults
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. Both samples were studied as part of the Persistent Effects of Treatment Study-Adolescent (PETS-A), conducted by the Center on Substance Abuse Treatment (CSAT)
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. Evidence of substance use in early adolescence has been shown to predict late adolescent substance use and adult maladjustment (Stacy & Newcomb, 1999; Brook, Balka, Gursen, Brook, & Shapiro, 1997; Newcomb & Bentler, 1988; Kandel, Simcha-Fagan, & Davies, 1986)
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. Should they tire, they could switch to moving the hand within a region on a surface
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