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Molten globule monomers have been proposed as intermediates in the dissociation of some dimeric proteins, including human superoxide dismutase (Silva et al
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The large-scale motion generated by backbone pivot moves ensures a lack of correlation between saved snapshots
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On screen a strange world of shiny white globules slowly disintegrates as a woman's voice tells the story of a tragic affair
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In a study (60) of the interfacial rheology of BLG, it was found that the protein formed a gellike elastic layer at the interface
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Bound to aggregated TTR, the fluorescence lifetime of both components have increased and the relative amplitude of the slower component has increased (Table 3), well in accordance with the massive increase in quantum yield compared to when bound to native TTR (Fig
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There was no problem obtaining a large amount of the monoclonal antibody required when identifying P
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Freely Diffusing Single Hairpin Ribozymes Provide Insights into the Role of Secondary Structure and Partially Folded States in RNA FoldingPljevaljcic, GoranABSTRACTSingle-molecule fluorescence resonance energy transfer studies of freely diffusing hairpin ribozymes with different combinations of helical junction and loop elements reveal striking differences in their folding behavior
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In summary, our comparative study of different ribozyme constructs shows that in contrast with the 2WJ and the 3WJ, the natural 4WJ architecture can efficiently guide conformational search events during ribozyme folding, thereby dramatically influencing subsequent tertiary structure formation and stability
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Detailing and samples, on the other hand, boost sales of a drug at the expense of similar drugs
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Clinically, the most important issue is consuming a variety of foods in manner that is healthy and sustainable
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About one in four Americans is enrolled in a Medco-managed drug plan
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of Pennsylvania School of Medicine), and Henretig (pediatrics and emergency medicine, U
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For the Nevers group, we assigned a random switching quarter to serve as their pre- and postpoint of reference
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Thus, across the two lagged waves, the total number of facility-year observations was 876
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BrownINTRODUCTIONIn 1996, the Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA) (1) was enacted with the goal of promoting the economic self-sufficiency of families by transitioning them from public assistance into the work force as early as feasible
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The average weight at the beginning of the program was 210
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McFarland (1987) characterized special languages as existing in particular forms
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The evidence suggests that the internet provides a new social niche for sexual expression
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Understanding across the sexual orientation gap: Sexuality as culture
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