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In particular denatured states of larger multidomain proteins quite often show up as more expanded structures with a strong tendency to form aggregates (1,2)
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. Overall, this category did not represent a large number of adults (8%)
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. Studies of cells in the laboratory have shown that drugs called ampakines elevate production of BDNF
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.It was also shown how molecular rotors such as DCVJ can be used as "aggregation probes" for amyloidogenic systems
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