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This two-stage scheme is similar to that from the chemical unfolding/ refolding studies of ACYI (18,19), which also indicated that there existed a dimeric, aggregation-prone folding intermediate
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. Since gSBA and rSBA both exist as tetramers with identical ligand binding specificities and macromolecular properties, the change of the mode of unfolding from a two-state process to a three-state process and the decrease of T^sub m^ by 26°C for the thermal unfolding of the protein of the kilter implicate the covalenlly linked glycans for the stability of gSBA
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. we plot ln([left angle bracket]R^sub ij^[right angle bracket]) versus ln(|j - i|) for four representative sequences drawn from Table 1
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. Deviations from the power-law scaling occur for internal distances between residues that areFor proteins in the EV limit, there are two distinct length scales
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. The aggregation reaction was initiated through a pulse of NaCl which induces the molten-globulelike A-state which subsequently assembles into aggregates
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