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Consequently, in the EV limit, a range of chain properties show so-called scale invariance
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Since the dealkylated soman moiety bound to the HuBChE monomer subunit contributes only three hydrogen atoms (P-CH^sub 3^) to the enzyme-inhibitor conjugate, while the deglycosylated native enzyme monomer itself accounts for >3500 nonexchangeable hydrogen atoms, the contribution of the inhibitor is negligibly small
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Since PLCß and G-protein subunits associate on membrane surfaces, we worked under conditions where the membrane surface properties are not expected to change
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Higher pressures (usually above 5 kbars) will result in penetration of solvent into the protein matrix, resulting in a molten globule (e
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After washing with PBS (100 [micro]L), biotinylated horse anti-mouse IgG (100 [micro]L) was added to the wells and incubated at room temperature for 20 minutes
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The peak position for the SL 3WJ remains in the low-FRET region of the histograms, independent of the Mg^sup 2+^ concentration, indicating that this ribozyme construct is incapable of folding to a compact structure (Fig
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"I had no clue what [meth] was
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The sustainability of pharmaceutical spending therefore depends not on outside forces but on decisions made by policy makers, prescribers, and patients
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"Employers are just not at the point where they want to discuss this openly," explains Dana Sohn, a media specialist at Chicago-based Aon Consulting
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military bases took form in East Africa, the Indian Ocean, and the Gulf
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This summer, the sco may agree to extend a membership offer to Iran
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PAY ATTENTION TO THE TABLE: If you concentrate only on your cards, you're failing to seize maximum opportunity toward improving your play
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The male pill: A biography of a technology in the making by Nelly Oudshoorn, a professor of gender and technology at the University of Twente in the Netherlands, reviews the history, philosophy, and social significance of this topic
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Among patients with echocardiographic evidence of worsened aortic regurgitation during follow-up, there were no reports of rales, murmurs, MI, pulmonary hypertension, heart failure, or chest pain
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N Engl J Med 2003;348:2082-2090
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Happy New Year!By Tony LisantiEditor/Associate Publisher
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For example, researchers have shown that, despite steep age-gradients in service utilization, population aging has explained approximately 1-2 percentage points of medical and hospital expenditure growth (Fuchs 1984; Barer, Evans, and Hertzman 1995; Reinhardt 2003)
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A large decline in hospital spending followed an expansion in the drug formulary of the South Carolina Medicaid program for an under age 65 population (Kozma, Reeder, and Lingle 1990)
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, Statistician, are with The Peter Lamy Center on Drug Therapy and Aging, University of Maryland School of Pharmacy, Baltimore, MD
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We included 15 predictors and 6 control variables
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9% at 3-, 6-, and 9-month follow-ups, respectively (12)
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5 Number Physicalof chronicfunctioning (d) conditions (e)Discrimination (N=809) (N=810)due toMeanp Mean pDrug Use0
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In the sample of affluent youth examined in this study, low parental closeness, combined with other adult supports were associated with higher rates of depression for boys and girls
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I said, 'Tryptanite? I've never heard of it
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There is evidence that depression does affect HIV risk-behavior change, although little is learned on the processes involved
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, is an assistant professor in the Department of Family Medicine, Ohio State University College of Medicine and Public Health
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Both sibutramine and orlistat have been evaluated in dozens of randomized, placebo-controlled trials and are shown to be safe and effective in properly selected patients, producing weight losses of 8-10% at 2 years (54, 55)
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For example, changing the color of text on a Web page by using Internet Explorer's built-in features requires knowing that Internet Options is the required menu selection from the Tools menu, then further being able to navigate to the Colors dialog box, deselect the Use Windows colors checkbox, set the desired colors, and then return to the Internet Options menu selection to indicate on the Accessibility dialog box that specified Web page colors should be ignored
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- the dimeric surface was losing hydrogen bonds (which yielded ??G = + 5
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.6 Hz in the ^sup 1^H and ^sup 15^N dimension, respectively
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. To confirm these assignments, we examined a destabilized 4WJ ribozyme variant, in which G^sub 11^ is replaced by inosine (I)
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