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In soman-aged HuBChE, the organophosphoryl moiety remains covalently attached to the unfolded protein, and the salt-bridge between the protonated imidazole ring of His-438 and the negatively charged phosphoryl oxygens may contribute to the observed shift in the onset of unfolding to a higher temperature compared to the native enzyme
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- Some factors in the interpretation of protein denaturation
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. Intestinal fatty acid binding protein: The folding mechanism as determined by NMR studies
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. It is known from various previous studies that for nearly all á-amylases both thermal and GndHCl-induced unfolding appear as an irreversible process (17-19)
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. Interactions of non-detergent sulfobetaines with early folding intermediates facilitate in vitro protein renaturation
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. After 48-h incubation, disk reconstitution is incomplete and a significant amount of lipid-poor apoA-2 is detected (lanes 9 and 10)
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.PeersAlthough peers have been shown to play an important role in various domains of social development (Rubin, Bukowski, & Parker, 1998; Coie, Dodge, & Kupersmidt, 1990), they have also been associated with negative outcomes for adolescents (Luthar & D'Avanzo, 1999; Dishion, McCord, & Poulin, 1999; Cauce et al
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