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The denatured state (the other half of the folding equation) and its role in protein stability
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. The three wavelengths yielded the same unfolding curves (data not shown)
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. Several amyloidogenic in vitro assays employ acidic pH for generation of amyloid fibrils; however, ThT shows very modest fluorescence at acidic pH when bound to protofibrillar amyloid of TTR (Fig
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. The large number of these, of order N times greater than the number of native interactions, make them a likely candidate for information storage, as well as their natural propensity for kinetic control
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. In short, the study staff used telephone survey procedures, which extensive research indicates will produce highly reliable and valid data (Groves et al
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. -The valves fell into 3 groups: 17 AVs and 28 MVs had fen-phen lesions only, 2 AVs and 7 MVs had fenphen changes associated with other valve diseases, and 16 AVs and 8 MVs had no fen-phen changes
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. Stimulant use and the potential for abuse in Wisconsin as reported by school administrators and longitudinally followed children
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. "If you can get transmission of the drug or the molecules through the skin osmotically, then just a simple patch would be the way to go," says Bob Andrews, Foster-Miller's medical division manager
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. "The Demand for Prescription Drugs as a Function of Cost-Sharing
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. To illustrate the effects of the other factors adjusted for in these models, in Table 5 we show the full model specification for the model that includes the discrimination due to drug use variable
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. Thus need and predisposing characteristics can be conceptualized as both predictors and outcomes of utilization over time
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. % zeroCurrent binge drinking (# of times3
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. Grant Foundation, the John D
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. Posters cannot talk to each other, and replies to questions come from automailers
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. Experts consider it a second-line drug
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. All of these individuals had protracted histories of obesity with failed dietary attempts
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. claimed content of ephedrine-type alkaloid dietary supplements have found substantial amounts of (+)-norpseudoephedrine, a schedule IV controlled substance, normally not allowed in nonprescription medications
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. (25) Referral to a psychiatrist who specializes in addiction should be considered when pharmacotherapy other than SSRIs is necessary
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- DISCUSSIONMolten globule (MG) folding intermediates have been characterized for a number of proteins (for reviews, see Kuwajima, 1989; Ptitsyn, 1992, 1995)
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.0 M NaCl where the dominant interaction is repulsive, the glasslike transition is primarily influenced by particle crowding (5,70)
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. Similarly, repetitive T-jumps with DMPC disks containing apoA-1 and apoC-1 show faster unfolding in the second and consecutive jumps (data not shown)
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. The features can be classified as: parallel tubular fibers, twisted ribbonlike structures, rod bundles, and ropelike textures
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. Positive stations formed scattered clumps along the whole distributional area of the species
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