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Here, we detected a maximum of ~0
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. Spectra were collected from 30°C to 98°C at intervals of 2°C with a spectral resolution of 4 cm^sup -1^ and 256 scans
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. In either case the conclusion is that in the frozen state the polypeptide structure of the putative binding sites has changed, becoming unable to host ANS or to enhance its fluorescence yield, as when the probe surrounding changes from rigid to mobile (26)
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. The second DSC peak is centered at 84°C, which is similar to the apparent T^sub m^ determined from the peak position in the first derivative of the CD melting data, d?^sub 222^(T)/dT (Fig
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. The enthalpic change upon gp120/CD4 complex formation, calculated as the difference in proteinprotein plus protein-solvent potential energy between the simulations of the complex and of the separate proteins (-127 kJ mol^sup -1^ at 300 K with a standard error, SE, of 11 kJ mol^sup -1^), is of the same order of magnitude as the experimentally determined value (-259 ± 13 kJ mol^sup -1^ at 310 K; Myszka et al
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. Docking of the two loops is also observed in simpler ribozyme constructs comprised of two- or three-way helical junctions (2WJ and 3WJ, respectively), although much higher Mg^sup 2+^ concentrations are required (N
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. Cost per prescription can be further broken down into two components: agesexMIX/Rx, the age/sex-specific mix of drug products selected per prescription within therapeutic categories, including changes in dosages selected; and PRICE/PILL, a price index for all products in each therapeutic category
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. "There is too much evidence that this practice biases the research in favor of the sponsor's drug" Indeed, in the January 2003 issue of the Journal of the American Medical Association, a review of a dozen studies evaluating conflicts of interest in medical research showed that industry-funded analyses of a drug are much more likely to turn out favorable than comparable studies conducted by scientists not funded by the industry
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- Due to the complexity of the investigated proteins (multitryptophan proteins in an ensemble of structurally heterogeneous unfolded states) a quantitative relation between ?^sub max^-values and the extent of aggregation or the compactness of the unfolded state cannot be given
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. The triglyceride peaks were better resolved, and small additional peaks-creatine, choline, and phosphatidylcholine at 2
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. (20), R^sub 2^ is measured for two settings of ? (we used 2?^sub 1^ = 450 µs and 2?^sub 2^ = 3
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. "Participation and Crowd Out in a Medicare Drug Benefit: Simulation Estimates
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.ConclusionsIn conclusion, it is remarkable that (possible) gender effects on motivation to gamble have not been previously reported as any gender differences found might offer additional insight to the primary motivation for both initial and sustained participation
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. However, skill-irrelevant factors, such as choice of machines, can be important even in games with low financial involvement, such as games on poker machines (Eisler, 1992)
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. Congenitally bicuspid aortic valves: surgical pathology study of 542 cases (1991 through 1996) and a literature review of 2,715 additional cases
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. Its effects are those of a classic psychostimulant, causing 'flying euphoria followed by a five-to-eight hour period of feeling tough, invincible with increased libido, and desire to be physical
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. Clinical indications for therapeutic use include treatment of narcolepsy, attention deficit disorder, and as an appetite suppressant in the treatment of obesity
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.4%, with ephedrine itself dominating the mix
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. Comprehensive follow-up may be provided by the primary physician, a registered dietitian, or a commercial weight control program (e
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. The increase was expected, but the size of the estimated effect is among the largest found in prior research, where estimates ranged from 18 to 60 percent (Leibowitz, Manning, and Newhouse 1985; Gianfrancesco, Baines, and Richards 1994; Gluck 1999; Lillard, Rogowski, and Kington 1999; Pauly 2004)
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.017thousands) N = 277N = 431Note
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. Aortic valves lacking fen-phen changes included 9 with calcific aortic stenosis, 2 with bicuspid AV, and the remaining 5 were due to either aortic pathology or were of unclear etiology
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.27 It is possible that drug-induced myofibroblastic proliferation induced by fenfluramine may continue after drug withdrawal as a response to endogenous serotonin
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."Navy COOL is for Sailors and it's all about professional development and Navy readiness," Hooley said
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