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For magic angle spinning (MAS) experiments, an indirect detection pulsed field gradient nano H{X} probe (4 mm) was used in a Varian (Palo Alto, CA) UNITY INOVA 500 NMR Spectrometer
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The most pathogenic transthyretin variant, L55P, forms amyloid fibrils under acidic conditions and protofilaments under physiological conditions
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To determine whether this could be the case for PLCß^sub 2^, we monitored the change in emission of CPM-PLCß^sub 2^ under pressure
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After HDL de-lipidation by guanidinium hydrochloride (Gdm HCl), apoA-1, and apoA-2 were isolated by FPLC as described in Wetterau and Jonas (1982)
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2) over a wide range of Mg^sup 2+^ concentrations
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Previous studies have found most changes in private health plans are because of external circumstances of different plan offerings or new enrollment opportunities rather than pure consumer choice (Cunningham and Kohn 2000; Stuart, Shea, and Briesacher 2001; Rice et al
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Future studies addressing these limitations can support better policies facilitating access to cost-effective drug treatment for all who need it
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ProcedureData for the seventh grade students were collected in classrooms during two 50-minute class periods on two separate days, in groups of 15 to 20 students
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She stood outside with a gaggle of other media people to announce her husband's triumph
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Another advantage of IE is a great variety of business add-ons available for it; the others have far fewer business extensions (but plenty for personal use)
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Richards is a research staff member and manager at the Thomas J
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Penal Code, these offshore virtual Monte Carlos offered interested parties the opportunity to wager 'round the clock
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There's perhaps no better example of this than Medicare
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Don Devine, a vice chair of the American Conservative Union who led a coalition of 30 fiscal conservative groups opposed to the bill, called the scenario a "lobbyist's dream
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Mayo and Wyeth-Ayerst announce plans to coordinate a new, multi-center fen-phen study
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Douglas JO, Munro IF, Kitchin Al, Muir AL, Proudfoot AT
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Amphetamine also has appetite suppressant effects and thus is used in the treatment of obesity, although it is not FDA approved for this use
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Drug Store News is published by Lebhar-Friedman, parent company of Connecting Northwest Arkansas
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83 in 2004 by selling more generic drugs, which offer 18% margin over brand-name
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21 The supernatant was removed and the resultant pellet cultures were treated for 48 hours at 37°C/5%CO^sub 2^ in a defined medium comprising of Dulbecco's Modified Eagles Medium, ITS+ Premix (Collaborative Biomedical Products: insulin (6
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However, the most scientifically supported uses are for male infertility and erectile dysfunction (ED)
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Our results suggest that discrimination is not one of these factors
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And we all know that obesity is not just a 2-year problem
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The market for weight loss drugs has fluctuated during the last 2 decades, spiking with approvals and dropping with high-profile recalls, said Laura Governale of FDA's division of surveillance, research, and communication support
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In order to use the debounce setting, though, users must know about this feature, be able to find and set it through menus and dialog boxes, and be able to specify the required debounce time in milliseconds
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EXE hoax making the rounds again
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- Besides, complex formation between GR and NADPH was only detected in the dimeric form of the enzyme, which would argue that NADPH does not participate directly in the process of GR folding/assembly
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. Since ACYI can maintain its dimeric structure at a high GdnHCl concentration of 2 M (18), it seems that the dimerization domain was quite stable against denaturation
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. This is in contrast with stabilization by kosmotropic buffers, which decrease the free energy of the native state
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. This timescale corresponds well with the expected motions of the N- and C-terminal CaM domains
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.MATERIALS AND METHODSPeptides and proteinsThe synthetic peplide corresponding to residues 86-105 of Gß^sub 1^ (NH^sub 2^-TTNKVHAIPLRSSWVMTCAY-CONH^sub 2^) and the corresponding control peptide that does not activate PLCß (Gß86-105(M101N)) were gifts from Dr
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. After HDL de-lipidation by guanidinium hydrochloride (Gdm HCl), apoA-1, and apoA-2 were isolated by FPLC as described in Wetterau and Jonas (1982)
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. 3, A and B, solid circles)
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. We derive here three further consequences: 3), early-time structure in kinetics; 4), nonnative contributions to ?-values; and 5), denaturant dependence and the interpretation of "Chevron plot" behavior
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. The mechanism appears to center around casein derivatives in cheese including glycomacropeptide
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.9-meter Anglo-Australian Telescope in Coonabarabran confirmed that hunch, he says
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. Based on the data displayed in Figure 1, the introduction of RP was not associated with any marked drops in the use of NSAIDs
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." In Patterns of Health Care in Ontario, 2d ed, edited by V
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."If you can get transmission of the drug or the molecules through the skin osmotically, then just a simple patch would be the way to go," says Bob Andrews, Foster-Miller's medical division manager
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. Perhaps, government agencies might facilitate similar mechanisms in the substance abuse treatment sector
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. "But when she first got out, she felt like everyone was out to get her
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. The typical profile is a person who has abused many drugs in many combinations for many years
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. Some studies indicate that boys are diagnosed with ADHD more often than girls by a ratio of 10 to 1
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. The FDA requested an independent review to assess causation and to estimate the level of risk these products pose to consumers
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.BEAR FACTS Estimates remain sketchy, but wild populations of Asiatic black bears seem to have dropped to about 15,000 animals throughout all of Asia, says Dave Eastham of the World Society for the Protection of Animals (WSPA) in London
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.Drug could be depression busterBruce BowerPreliminary evidence indicates that a single dose of a drug called ketamine rapidly quells symptoms of major depression for up to 1 week in patients who don't benefit from standard antidepressant medications
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. There was usually a male in the family who could serve as a role model--if not the father, then a grandfather, older cousin, or uncle
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. Journal of Studies on Alcohol, 57, 289-304
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. The release of stored neurotransmitters can be triggered directly when psychostimulants bind receptors present on neurons or can release neurotransmitters indirectly via an exchange mechanism occurring through monoamine transporter proteins
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. However, even though there was an increase, the overall numbers of related visits in these areas remained low
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. The internet appears to have taken this further, where the "property" is ultimately taken to the extreme of malleability, plasticity and transience
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. Central methodological questions that relate to external validity include population issues: who is using the internet? How do they differ from the broader population? How do those sampled on the internet differ from those using the internet? Construct validity questions include those relating to what the mechanism underlying internet responses is, and whether it may differ from supposedly similar constructs in a face-to-face setting
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. Gender swapping on the internet
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.The Web Adaptation Technology application, a platform-dependent set of extensions for Windows Internet Explorer, was developed first
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