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Stabilization of proteins by glycosylation examined by NMR analysis of a fucosylated proteinase inhibitor
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Because efferocytosis appears to be a key regulatory checkpoint for the innate immune system, the adaptive immune system, and cell proliferation, the failure of this highly conserved process may contribute to disease pathogenesis by impeding both the resolution of inflammation and the maintenance of alveolar integrity
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Compounds that alter the Rac-1/RhoA balance, by either increasing the level of active Rat-1 (preferable) or decreasing the levels and/or activity of RhoA/ Rho kinase, would be potential candidates for use in therapy
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Nature 2000; 405:85-90(26) Cikala M, Alexandrova O, David CN, et al
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Proteins which do not present a single cooperative system
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It was then suggested that PLCß^sub 2^ binds to Gß?-subunits through several strong contacts, but that activation proceeds through more subtle, weaker contacts
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Additionally, only this ribozyme is almost completely docked at physiological concentrations of Mg^sup 2+^ (~2 mM)
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50It's a boost of color that feels silky and luxurious, yet resists fading, thanks to its triple-patented gel-based formula
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Parsons reserves his greatest concern for the third type of error--paying for brand-name drugs rather than less expensive generic substitutes
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Examples of numerous questionable cases include:* $12,000 for annual Oxycontin use for a 1990 workers' compensation claim of neurotic depression
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This group was necessary to address an MCBS data limitation of providing drug-spending levels at only the annual level while the duration of drug coverage spanned one to eight quarters
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" Our measure of current sexual behavior is based on responses to the questions "During the last 12 months, with how many partners do you estimate you have had sexual intercourse?" Sex in high school is defined by a "before college" response to the question "When did you have sexual intercourse for the first time?"Control VariablesCIRP measures used as control variables in our regressions include both self and roommate responses to questions about: (i) years of father's education; (ii) years of mother's education; (iii) high school grade point average; and (iv) family income
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An additional encouraging finding was the fact that their emergency networks increased over time
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"And every eight years in those counties that opted for gaming, it has to come back to the polls again
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Mok, who works for the General Women's Association of Macao,said her life has remarkably improved since new casinos opened in2004 and 2005
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2K & Treatery($30K) All American Specialty23/0$110K-244K Restaurants Inc
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"We ended up with a program that undermines Medicare and costs way too much for a program with major gaps in coverage," said Roger Hickey, co-director of the Campaign for America's Future and a founder of Americans United, a coalition of consumer and labor groups demanding that Congress fix the plan
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Experts consider it a second-line drug
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Not only did new software need to be developed to run the automated plant, but a new system had to be devised to accept and process prescriptions in high volumes
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For example, neem extracts and essential oils have been used for centuries to treat all manner of skin conditions, including ache, eczema, psoriasis, warts, athlete's foot, and chicken pox
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When was the last time an NEJM editorial used a negative drug study to argue that no one should take, or even perform scientific research on, pharmaceutical products?Alan R
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) Berkman L, Glass T
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New York: Oxford University Press, 2000:36-75
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) Braddock JH II, McPartland JM
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Also available in sustained-release formulation
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SAThe Internet contains a bewildering number of sources on every imaginable topic
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, adding an option for increasing text size beyond what the browser could support directly), and enhance feature usage through keyboard navigation
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[FIGURE 4 OMITTED]In other applications, tools were developed to control the mouse pointer
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comRent Stabilization Association:www
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- Thus, it seems reasonable to expect that the monomers of yeast GR may also be catalytically inactive and that dimerization may be critical for enzyme activity
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. Borowsky and Wilkens also discovered that one of those genes is closely linked to a gene that regulates metabolic rate (it is even possible, though unproved, that both eye development and metabolism are affected by one gene)
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. We refer to these plots in the following as Guinier plots, due to their analogy to the Guinier plots in SAS
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. MSDs increase continuously, but display a dynamical transition at ~200 K
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. 3, A and B, indicates that, in apoA-2:DMPC complexes, protein unfolding precedes fusion, suggesting only loose coupling
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. Although the overall numbers are not quite as lopsided as they were in the Tulia sting, there's no denying that blacks, who are no more likely than whites to use illegal drugs, are over-represented among drug offenders who get arrested and go to prison: More than 60 percent of imprisoned drug offenders are black, five times the percentage of blacks in the U
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. Data from the Monitoring the Future study show that while in high school, college-bound students use less of all classes of substances studied as compared to classmates not bound for college (Bachman, Wadsworth, O'Malley, Johnston, & Schulenberg, 1997)
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. sales of Bicycle playing cards were up 30 percent last year, and demand for poker sets doubled, according to U
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. The new web site, which went online in early June and will be fully populated over the summer, will include information to make it the Leading resource for those interested in patient safety issues
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. Among Super Seal's features is a quick-change design to accommodate customized sealing heads for added flexibility if package configurations change
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.Phentermine works to release dopamine and norepinephrine, while sibutramine facilitates serotonin and norepinephrine release
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.Central-fill expansion is prescription for success - Pharmacy Automation - Industry OverviewThe shift in retail pharmacy to filling and processing select prescriptions centrally is picking up momentum in what one source described as "proof of the concept's viability
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.Ben Loy, senior vice president of industry relations for PDX-NHIN, said the HIPAA regulations that require the capturing and documenting of signatures from patients who have been told about their privacy rights could potentially cost retailers hundreds of millions in labor costs and materials
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. Treatment effects for males were trivially small and not statistically significant (b=58, z=1
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. Government officials and social conservatives worry that information about drugs will sway impressionable youngsters into using them
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. Thus, we proposed adding a depression therapy component as an adjunct to a social network HIV/drug use risk reduction intervention
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.8 MDMA has received much negative attention in recent years as claims of its neurotoxicity mounted
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. In the current version, Mozilla's XUL language does much of this work for us
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. Of course, new features do not include image-handling features only
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