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Theory and experiment make it unequivocally clear that the ensemble accessible under these harshly denaturing conditions need not bear resemblance to the nonnative states accessible to proteins under more physiological conditions
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. Since the folding process is complex in multidomain proteins, where each domain may be able to refold independently and interdomain interactions may affect the overall folding process, EI can be used, in addition, as a model protein to improve our knowledge of protein folding and assembly of multidomain-oligomeric proteins
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. 1 M potassium cyanide and 1 mM EDTA in 0
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. Estimating the time scale of chemical exchange of proteins from measurements of transverse relaxation rates in solution
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. DCVJ was found to be very sensitive to formation of early oligomers and showed the strongest apparent binding affinity of the probes in the study
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. Arrhenius plots for these phases are linear and intercept near 100°C (Fig
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. Periodo diciembre 2000 a marzo-abril 2001
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. Entropy calculations on the molten globule state of a protein: side-chain entropies of ?-lactalbumin
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. Such a predisposition may not be enough to cause oxidation during mix storage, when exposure to oxygen is minimal
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. To calculate the time until parturition for each stage, we subtracted the previous stage durations from the total gestation period of 37
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. We found some support for our prediction that units affiliated with hospitals or mental health centers would be less likely to engage in IORs (H5)
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. In particular, the XML (Extensible Markup Language) User Interface Language (XUL **) feature of this environment permits the runtime assembly of complex user interface elements
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. Today's gambling opponents often suggest that gambling has been pushed upon an unwilling public by revenue-starved politicians and their greedy industry benefactors
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. If the player had blackjack, and the dealer had an ace or a 10, then the computer could not draw a 10 or an ace for the second card
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. , the player could not bust), and the cards to the dealer would either produce a smaller total than the player or bust
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. ((Comments on this story may be sent to info@m2
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. Recent data suggest that obesity accounts for 14-20% of all cancer deaths, making it second only to smoking in terms of modifiable risk factors for cancer mortality (11)
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. Indeed, noted CMS, at least one prescription drug plan in every state but Alaska will offer Medicare enrollees who join a premium of less than $20 per month versus the $32 average premium that federal planners expected the PDPs to charge
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. " Drug and Alcohol Dependence 57: 151-66
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. J Health Polit Policy Law August 2000; 25(4):623-647
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. Like Knox, Hurwitz attracted attention largely because of his OxyContin prescriptions
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. 38 Because of the growing number and consistency of ephedrine-type alkaloid AERs (outlined above), combined with the then virtual absence of publicly available safety data, the FDA convened an ad hoc Working Group to study the issue
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. McRae (1996) has also noted the similarity of net sex to the medieval concept of courtly love
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- Hence, these scans were not employed tor the calculation of the thermodynamic parameters for the unfolding of proteins
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. The activity of EI is regulated by a monomer-dimer equilibrium, where the autophosphorylation requires the dimeric species (2-4)
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