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It is generally assumed that two distinct enzymes are involved in the intracellular degradation of N-acetylated proteins: the N-acetylated peptide hydrolase catalyzes the hydrolysis of the N-terminal amino acid residues from the N-acetylated proteins causing the release of acetylamino acids, which are finally hydrolyzed by ACYI (10,11)
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This simultaneous unfolding is strongly pH-dependent, and at high pH
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15 M Tris-HCl, pH 8, followed by column chromatography (23)
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Upon freezing the sample, the ANS intensity first decreases in the low concentration range, below 80 µM, but then rises sharply above this threshold
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It should be noted that the diminazene aceturate concentration we used for the cellular uptake experiment is relatively high (250 mM) but still not even half a percent of the concentration of water which dominates the MR signal
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Observations on the subcellular distribution of the ammonium ion in maize root tissue using in-vivo ^sup 14^N-nuclear magnetic resonance spectroscopy
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The model also shows that high-dimensional structures provide conceptual relations between different models of protein folding
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The flexible resin gave the required textile properties, so the study concluded that an investigation of alternate methods for producing xerographic textile-specific toners from flexible resins should be conducted [20]
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The products were unlawfully imported and falsely labeled as Advantage and Frontline, products regulated as insecticides by the U
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2 percent for children (average annual rates of 0
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, Assistant Professor, Centre for Health Services and Policy Research, University of British Columbia, 429-2194 Health Sciences Mall, Vancouver, BC, Canada V6T 1Z3
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(3) Silverscript is a subsidiary of Caremark
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Previous empirical studies provide some support for the logic outlined above
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DISCUSSIONThe recent proposed strengthening of welfare reform policies necessitates the study of factors that may contribute to the successful transition from welfare to work
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Our target sample size for the pilot study was 15 subjects; however, given the attrition rates of subjects in the SAFE study, we recruited 29 subjects for the baseline interview
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The Osprey is currently limited to 60 degrees of bank and 20 degrees nose up but that envelope may be increased to enhance survivability
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Fen-Phen Valve Disorders Don't Worsen Over Time - Brief ArticleBruce JancinNEW ORLEANS -- The natural history of valvular heart abnormalities in patients treated with dexfenfluramine or phentermine/fenfluramine appears more reassuring than earlier feared, according to the results of the largest controlled, blinded study to date
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By the time he presented in October 1999, his weight had reached an all-time high of 335 lb
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According to Tabouchirani, only about one-third of children take their medications as directed
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Under new Congress-mandated rules, CMS will scrap its reliance on the average wholesale price, or AWP, of a drug when determining reimbursement rates for pharmacies that dispense prescriptions to patients covered by Medicaid
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"The new pharmacy design, like every change within the stores, according to Chomiuk, is based on "a lot of research
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ClearRx: art project to retail pharmacy conceptAntoinette AlexanderNEW YORK -- When graphic designer Deborah Adler learned that her grandmother accidentally took prescription medication meant for her grandfather, she flipped--the pill bottle, that is
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Operational Issues in Incorporating Complementary and Alternative Therapies and Providers in Benefits Plans and Managed Care Organizations
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Many of the prescription drugs used by Medicare beneficiaries are taken over the course of many years to slow the effects of disabling disease and thus related changes on demand for medical services may share a similarly lagged effect
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090High school grade point average -1
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The CES-D Scale: a self-report depression scale for research in the general population
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As a science, forensic toxicology deals with the medico-legal implications of drug use, misuse, and abuse
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Service-oriented architectures bring an opportunity for moving toward a clearer separation of interface components from the underlying data sources
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This is the case with the SUFLNBK hoax
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com are a result of our listening to our customers' feedback and designing new features to improve their online shop ping experience," said Chris Shimojima, vp and gm of Customer Direct for Sears Holdings Corp
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- Role of osmolytes as chemical chaperones during the refolding of aminoacylase
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. Stability of EI^sup sc^ as monitored by DSC and thermal denaturations From the spectroscopic results above, it can be concluded that EI^sup sc^ acquired a folded conformation around physiological pH, and that this structure was basically unaltered (exeept for changes in the ellipticity, Fig
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. Among them LDH, ?-amylase, and ß-gal have in the past been the subject of freeze-thawing inactivation studies (13-17)
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. For typical membrane concentrations used in these studies, the apparent K(d) should be ~200-fold stronger than the true K(d) (see Runnels and Scarlata, 1999)
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. 1 B and by their independence of the scan rate), the heating and cooling curves of the apoA-2:DMPC complexes show hysteresis that was also observed in DMPC complexes with apoC-1 (Gursky et al
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.In contrast to the 60°C incubation, in which a fibril concentration increase of ~1:4 (235 fibers versus 325 fibers) can be determined in the time period between 1 day and 1 week, a noteworthy fibril concentration change at 70°C in the same period does not take place
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.Medications such as phentermine (Fastin), phenylpropanolamine, ephedra, and sibutramine (Meridia) are systemic psychostimulants with the potential for abuse or addiction, and should not be used in recovering patients
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.Toyota may view the high usage as a positive, but it is certain that many employees did not appreciate the longer wait times
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.8 A recent development of the ACI procedure, termed matrix-induced autologous chondrocyte implantation (MACI), involves seeding the cells into a collagen membrane which is cultured in vitro for a few days prior to implantation
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. Future research should more directly test these relationships
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.Regardless of socioeconomic status (SES), adolescents experience increased rates of depression and substance use as they enter their teen years (Hankin et al
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