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Since the folding process is complex in multidomain proteins, where each domain may be able to refold independently and interdomain interactions may affect the overall folding process, EI can be used, in addition, as a model protein to improve our knowledge of protein folding and assembly of multidomain-oligomeric proteins
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Fluorescence spectroscopy Intrinsic fluorescence was measured using a RF-1501 rluorospectrometer (Shimadzu, Duisburg, Germany) and a LS55 luminescence spectrometer (Perkin-Elmer, Rodgau, Germany)
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4) and stored in OR2 buffer (82
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19 [Angstrom]^sup -2^ RESULTSMean-square displacementsDmAChE-H2O versus HuBChE-H2OFig
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We conjecture that holding at 160°C destroyed undissolved nuclei in the solution, and when the solution was cooled, fewer but larger particles were formed
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Assuming this relationship of fork length to maturity had not changed over time, we applied our logistic model to fork-length data from random sampling conducted by ODFW during the summers of 1992-2000 to calculate the percentage of female black rockfish caught by the recreational fishery off Newport that were mature in each year
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The inability of two- and three-way junction ribozymes to fully populate a docked conformation reveals the importance of correct helical junction geometry as well as loop elements for effective ribozyme folding
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The study was approved by the Food and Drug Administration in December, and the Drug Enforcement Administration was expected to issue the required federal license after a March visit to the research site
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t] the average beneficiary expenditures per day of NSAID therapy dispensed, and multiplying the estimated price changes by the total days of NSAID therapy dispensed
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"Inventory of Studies on the Accuracy of Canadian Health Administrative Databases
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extemely high body temperature
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There was no relationship, however, between percent of clients covered by Medicaid and IORs
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013 *H3: Managed careparticipation([section])-0
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She received a B
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This is mostly, but not entirely, unfounded
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He's got the walk of a casino boss--and the charisma to match
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Outside the Sheraton Hotel in Arlington, Virginia, rain is pouring in nearly biblical quantities
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In contrast, the no-advice players showed no obvious trend except that they sat on higher totals in the last four blocks than in the first four blocks
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One of these players, 23-year-old David Williams, took second place and a prize of $35 million
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Probably, as suggested by Eisler (1992), the biggest concern of players of computerized games is the assurance of fair play rather than control
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All C, F426Golf USA Inc
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) Meckling KA, O'Sullivan C, Saari D
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In accordance with approved labeling, only obese patients should take these drugs, and they should also follow a weight-loss regimen that includes a reduced-calorie diet and an exercise program
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Advisory panel members said trials should be large enough to flag safety problems in 1 in 500 patients
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We show that persons who used drugs more frequently were in poorer mental health (see Table 5), which may be a function of their having increased exposure to discrimination (although there are other potential explanations for this association)
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There also is some question surrounding the definition of an authorized distributor of record
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And if a guy does communicate with his girlfriend or wife about porn, and she wants no part of it, he may very well continue to watch in secret
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((Comments on this story may be sent to info@m2
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One might contrast the internet, as one electronic medium, with the telephone, as another, to highlight Giddens' (1992) point
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NET) Web service client demonstrator application
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- of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, PR China
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. Beyond local length scales, chain properties follow well-defined power laws that are expected for generic polymers in the EV limit
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. Principles of Polymer Chemistry
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. When we examined BAL fluid from COPD patients, we found increased numbers of apoptotic cells and decreased numbers of apoptotic cell ingestions, which is consistent with an efferocytosis defect (W
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. Rotational diffusion anisotropy of human ubiquitin from ^sup 15^N NMR relaxation
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. Protein aggregation and amyloid formation in vivo and in vitro are very complex processes which require sophisticated techniques for appropriate understanding and for future development of diagnostic tools and assays for high throughput drug screening
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.Source: Drug Store News and Chain Store Guides research
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. After FDA approval, competitive drug companies can only sell generic versions after the usual 20-year patent on the brand-name drug has expired
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.Ramsey believes next year will represent a "more level playing field for marketers and sellers of all sizes, across all industries
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.Aside from lesser copays, there's no denying that on-site pharmacies can be beneficial in other ways
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. The types of stressors section is comprised of five categories (frustrations, conflicts, pressures, changes, and self-imposed)
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. A lack of perceived openness between patients and their physicians may contribute to patients not sharing information with their physicians and may result in poor coordination between clinician-initiated therapies and those patients start on their own (Mootz and Bielinski 2001; Hsiao, Wong, and Kanouse 2003)
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. Another study measured stomach-acid secretion in people with ulcers, then gave them neem bark extract (30 milligrams twice a day)
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. "I've seen it work in lowering cholesterol," says Duke
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. Newborns were included in the cohort aged 2 and under, and residents aged 91 and older were combined in a single 91+ cohort, yielding a total of 92 age/sex cells in the population frame
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.There was some evidence that drug abuse treatment facilities used IORs to respond to proefficiency expectations of payers
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. It's perhaps the boldest call yet for reform
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." She was placed on a maintenance program that continued the daily intake of 1200 Cal but decreased the soy-based medical food to only one serving per day
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. She was no longer hypertensive and maintained her BP at 128/80 mm Hg
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. Drug Alcohol Depend 1986; 17: 169-92
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