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the high mannose GlcNAc^sub 2^Man^sub 9^ glycan chain was attached with Asn-75 (N?2) of the protein (Protein Data Bank code 2SBA) using MOE (Molecular Operating Environment) software, and energy was minimized using a force field of AMBER99
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. As described in more detail below, the present invention comprises the multistep precipitation process plus a subsequent heat treatment
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. Such case reports are rare,15 and psychiatric complications generally result in psychosis and affective disturbances
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. In general, most ephedrine-type alkaloid products, regardless of their promoted use, have ephedrine-type alkaloid levels at or above 10 mg per serving
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. The model elements are same as for equation (1) except the Z variables have been replaced by a single indicator of postenrollment observations, and the main effect of being a Gainer has been added as R and specified below:[Y
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. (42) Similarly, apoptotic cell ingestion in vitro and in vivo increases HGF release from both alveolar macrophages and airway epithelial cells
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. This trend is consistent with a pronounced binding capacity of oligomers whose subunits tend to dissociate in frozen aqueous media thereby making accessible large hydrophobic patches of the subunit interface
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. Indeed, several lines of evidence indicate that both pressure-induced and thermal denaturation of HuBChE are multistep processes that are initiated by penetration of water into the active-site gorge, leading to protein swelling and, eventually, unfolding (18,53,54)
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., at the tips of the N- and C-terminal domains, ii), close to the hinge region connecting the N- and C-terminal domains, iii), close to the hydrophobic pockets in the N- and C-terminal domains where the target binds (see Fig
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. 1, A''-C'', we calculated the ratios of DNA in the coil and globule conformations
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. The most rapid components had lifetimes Time-resolved fluorescence anisotropy was employed to probe the dynamics of different conformational states of TTR
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. This suggests that the cooperativity unit in this transition comprises a single copy of lipidated apoA-2 rather than the entire lipoprotein
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., 2004), and LDL (Jayaraman et al
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. Consistent with this hypothesis, previous trFRET studies have shown that the 4WJ stabilizes the tertiary structure of the hairpin ribozyme by reducing the entropie penalty for docking as compared with ribozyme constructs containing either a 2WJ or 3WJ (Klostermeier and Millar, 2000)
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.t] = 1] - E[[DaysNSDPop
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. Sixty-four cases comprising a total of 78 valves (35 AVs, 43 MVs) that met these criteria were identified
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