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INTRODUCTION The development of an accurate theoretical framework for describing denatured-state ensembles of proteins has been a topic of long-standing interest (1-12)
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Binding of the catabolite repressor protein to its DNA target is regulated by phopshorylation of its co-represser HPr
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This novel mode of target-specific binding, which neither belongs to lock-and-key nor induced-fit binding, is characterized by dimerization and continuous exchange between multiple flexible binding alternatives
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These points and the liquid-glass transition boundary have been added to the nonequilibrium phase diagram (Fig
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Improving the density of jammed disordered packings using ellipsoids
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, he prided himself on how conscientiously he selected the drugs that he prescribed
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The treatment groups also did not differ significantly with respect to the proportion of participants receiving mental-health care at either 6- (p=80) or 9-months (p= 1
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Unfortunately, the GAIN did not contain a wide array of treatment related cognitions
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The amount of money Americans spend on drugs each year has tripled in the past decade and is the single largest reason the cost of health care is rising at double-digit rates each year
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) Galaif ER, Newcomb MD, Carmona JV
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Each prescription of a controlled substance can be made into several crimes
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Tiger's going to beat me, or he's not
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The book has several significant strengths
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When catecholamine receptors in the brain are activated, myriad effects can result
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Many of these AERs occurred in young, healthy adults considered unlikely candidates for such events; 56% of these cases involved individuals less than 40 years old, 92% of these events were related to the use of products marketed for weight-loss and energy purposes, and 5% were related to products marketed for athletic-enhancement purposes
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We designed an intervention targeted at a high risk subpopulation of depressed active injectors--the MINERVA (Multidisciplinary Intervention for Needle Users to Reduce Viral Acquisition) study
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Griffith said some local churches have used the program to help poor and needy families in their areas
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J Clin Endocrinol Metab June 2003;88: 2462-9
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This is mostly, but not entirely, unfounded
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- A hypothesis for the pathway of the thermally-induced unfolding of bovine pancreatic ribonuclease
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