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Protein dynamics, folding and misfolding: from basic physical chemistry to human conformational diseases
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. As noted by Chan and Dill in their influential review (37), theories drawn from the polymer physics literature (38-44) are well-suited to describe heterogeneous conformational ensembles such as those of denatured slates
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. 3 M^sup -1^ and v = 0
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. Despite these features the overall interaction is highly specific with nanomolar binding strength (16)
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. The gp120 molecule without the V3 loop and the CD4 molecule, both using all atoms (code: all) or using only backbone (N, C?, and C') atoms (code: bb); see Fig
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. Here we present a systematic study of the folding behavior of hairpin ribozymes containing different combinations of loop and helical junction elements
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- Two-dimensional correlation sSpectroscopy: effect of hand position, width, and intension changes on correlation intensities
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. The intermediate and high q regimes provide the most information regarding average chain shape and fluctuations (62-64)
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. Predicting the energetics of osmolyte-induced protein folding/unfolding
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. The intensity of positive immunostaining was generally moderate but was not graded
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. More than 1,000 African Americans in the trial showed significant improvement with the drug," he said
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. 2000; Orlando, Chan, and Morrall 2003)
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.[FIGURES 1-8 OMITTED]To determine whether mother closeness buffered against low father closeness for boys and whether father closeness buffered against low maternal closeness for girls, the interactions were examined
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.PeersAlthough peers have been shown to play an important role in various domains of social development (Rubin, Bukowski, & Parker, 1998; Coie, Dodge, & Kupersmidt, 1990), they have also been associated with negative outcomes for adolescents (Luthar & D'Avanzo, 1999; Dishion, McCord, & Poulin, 1999; Cauce et al
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. CMS hopes those rewards will be enough to coax companies that currently do not offer drug benefits to alter their stance
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. In addition, social networks that are unsupportive of drug abstinence may encourage relapse among those returning home after drug treatment (32)
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.Reed, who also serves as Southeast regional chairman for the Bush-Cheney campaign, received the fees from two lobbyists whose ties to the Indian tribes are now the subject of a federal investigation
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." Carter, in 1980, restated the doctrine even more forcefully: "Let our position be absolutely clear
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. ofMean MedianItems Score *Score *Awareness and10 6972openness toworking withpractitionersfromother paradigmsReadiness to7 6467refer patientsto otherparadigmsLearning from 5 4340alternateparadigmsPatient-centered3 7375careSafety of 5 7480integrativemedicineClinicians'30 6466orientationtowardIntegrativeMedicineScale (IM-30)Scale/Domain SDSkewness % Scoring of ScaleMinimum([dagger])Awareness and20-0
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